KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESPL1
All Species:
10
Human Site:
T494
Identified Species:
31.43
UniProt:
Q14674
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14674
NP_036423.4
2120
233113
T494
L
G
L
V
K
P
G
T
Y
P
E
V
P
P
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103494
2120
233105
T494
L
G
L
V
K
P
G
T
Y
P
E
V
P
P
E
Dog
Lupus familis
XP_849828
2116
232497
T501
L
G
L
A
K
L
G
T
Y
P
E
L
P
P
E
Cat
Felis silvestris
Mouse
Mus musculus
P60330
2118
233016
A489
L
G
S
A
T
S
G
A
C
P
E
V
P
P
E
Rat
Rattus norvegicus
NP_001164073
2109
231597
A489
L
G
L
A
K
S
G
A
C
P
E
V
P
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423289
1597
172559
L109
K
Q
L
L
Y
H
S
L
Q
L
F
T
S
V
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001337869
2182
240839
S479
L
C
K
D
C
P
P
S
L
P
M
D
R
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782226
2231
246313
S533
Q
A
W
Y
D
F
A
S
S
L
V
R
L
A
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.9
82.3
N.A.
77.3
77.8
N.A.
N.A.
27.1
N.A.
34.6
N.A.
N.A.
N.A.
N.A.
22.4
Protein Similarity:
100
N.A.
97.7
88.2
N.A.
85.4
85.7
N.A.
N.A.
40
N.A.
52.3
N.A.
N.A.
N.A.
N.A.
40.7
P-Site Identity:
100
N.A.
100
80
N.A.
60
73.3
N.A.
N.A.
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
100
86.6
N.A.
60
73.3
N.A.
N.A.
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
38
0
0
13
25
0
0
0
0
0
13
13
% A
% Cys:
0
13
0
0
13
0
0
0
25
0
0
0
0
0
13
% C
% Asp:
0
0
0
13
13
0
0
0
0
0
0
13
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
63
0
0
0
63
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
13
0
0
0
0
% F
% Gly:
0
63
0
0
0
0
63
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
0
13
0
50
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
75
0
63
13
0
13
0
13
13
25
0
13
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% N
% Pro:
0
0
0
0
0
38
13
0
0
75
0
0
63
63
0
% P
% Gln:
13
13
0
0
0
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
13
13
0
0
% R
% Ser:
0
0
13
0
0
25
13
25
13
0
0
0
13
0
0
% S
% Thr:
0
0
0
0
13
0
0
38
0
0
0
13
0
0
0
% T
% Val:
0
0
0
25
0
0
0
0
0
0
13
50
0
25
0
% V
% Trp:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
13
0
0
0
38
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _